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  • A developmental route to hematopoietic stem cells

    A developmental route to hematopoietic stem cells

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    Stem cells

    Nature Biotechnology (2024)Cite this article

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    A differentiation method informed by developmental biology converts human pluripotent stem cells to engraftable hematopoietic stem and progenitor cells without the use of transgenes.

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    Fig. 1: Recently published protocols for the generation of hematopoietic stem cells from human pluripotent stem cells in vitro.

    References

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    Author information

    Authors and Affiliations

    1. MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, United Kingdom

      Adam C. Wilkinson & Marella F. T. R. de Bruijn

    Corresponding authors

    Correspondence to Adam C. Wilkinson or Marella F. T. R. de Bruijn.

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    Competing interests

    The authors declare no competing interests.

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    Cite this article

    Wilkinson, A.C., de Bruijn, M.F.T.R. A developmental route to hematopoietic stem cells. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02398-7

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    • DOI: https://doi.org/10.1038/s41587-024-02398-7

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