What will it take to get miRNA therapies to market?
Technology tamfitronics The Nobel Prize in medicine was awarded for the discovery of miRNA, but miRNA therapeutics have a long way to go before they outcompete other therapies. The Nobel Prize in Medicine was awarded in early October to Victor Ambros and Gary Ruvkun for discovering how microRNAs (miRNAs) have central roles in gene expression by binding to target mRNAs and inhibiting their translation. Since their discovery in 1993, miRNAs have been found to influence gene expression pathways in cell differentiation, proliferation, and survival. Years of research have been done to understand how genetic pathways are directly influenced by miRNA binding and how these pathways are interrupted when miRNA expression becomes abnormal, leading to disease. However,...
